NLRP3 polymorphism is associated with protection against human T-lymphotropic virus 1 infection
نویسندگان
چکیده
منابع مشابه
NLRP3 polymorphism is associated with protection against human T-lymphotropic virus 1 infection
Inter-individual heterogeneity in the response to human T-lymphotropic virus 1 (HTLV-1) infection has been partially attributed to host genetic background. The antiviral activity of the inflammasome cytoplasmic complex recognises viral molecular patterns and regulates immune responses via the activation of interleukin (IL)-1 family (IL-1, IL-18 and IL-33) members. The association between polymo...
متن کاملEvaluating the Frequency of Human T-Lymphotropic Virus Type 1 Infection in Iranian Population
Background: Human T-cell lymphotropic viruses 1 (HTLV1) is endemic in specific regions. We aimed to determine the prevalence of HTLV I infection among blood donors in southeast Iran. Methods: This cross-sectional study was conducted between April 2005 and March 2015. Sera were collected from blood donors and were tested for the presence of HTLV1 specific antibody using ELISA. Reactive sample...
متن کاملBronchiectasis is associated with human T-lymphotropic virus 1 infection in an Indigenous Australian population.
BACKGROUND Recent studies suggest that infection with human T-lymphotropic virus 1 (HTLV-1) might be associated with bronchiectasis among Indigenous Australians. The present study compared the clinical characteristics and outcomes of bronchiectasis in this population, according to HTLV-1 serologic status. METHODS We performed a retrospective cohort study of Indigenous adults with bronchiectas...
متن کاملIs human T-lymphotropic virus type 1 infection associated with hearing loss?
OBJECTIVES/HYPOTHESIS Human T-lymphotropic virus type 1 (HTLV-1) infection is endemic in the northeast area of Iran. Although various neurological disturbances have been reported in HTLV-1 infection, possible audiovestibular involvement during this infection has not yet been studied. STUDY DESIGN Case control study. METHODS Sixty-eight cases in three groups including 24 HTLV-1-infected pati...
متن کاملTuberculosis and human T-cell lymphotropic virus type 1 infection.
SIRIn a recent review of the infectious complications of human T-cell lymphotropic virus type I (HTLV-I) infection, Marsh [1] suggested that those individuals infected with HTLV-I may be at increased risk of tuberculosis. This risk may be due to reduced delayed-type hypersensitivity to PPD in asymptomatic patients infected with HTLV-l. Up to 14% of the population in Papua New Guinea are infecte...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Memórias do Instituto Oswaldo Cruz
سال: 2014
ISSN: 0074-0276
DOI: 10.1590/0074-0276140154